Coronaviruses primarily infect the upper respiratory and gastrointestinal tract of mammals and birds. The most publicized human coronavirus is SARS, which has a unique pathogenesis because it causes both upper and lower respiratory tract infections and can also cause gastroenteritis. Coronaviruses are believed to cause a significant percentage of all common colds in human adults. Transmission is thought to be aerosol, which means person to person transmission through air. It can survive up to 24 hours on metal surfaces, so steam sterilization of an environment should be considered to neutralize the virus.
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Coronaviruses also cause a range of diseases in farm animals and domesticated pets, some of which can be serious and are a threat to the farming industry. Economically significant coronaviruses of farm animals include: porcine coronavirus (transmissible gastroenteritis coronavirus, TGE) and bovine coronavirus, both of these cause diarrhea in young animals.
Feline Coronavirus has two forms. Feline enteric coronavirus is a pathogen of minor clinical significance, but spontaneous mutation of this virus can result in feline infectious peritonitis (FIP), a disease associated with high mortality.
There are two types of canine coronavirus (CCoV), one that causes mild gastrointestinal disease and one that has been found to cause respiratory disease.
Mouse hepatitis virus (MHV) is a coronavirus that causes an epidemic murine illness with high mortality, especially among colonies of laboratory mice. Prior to the discovery of SARS-CoV, MHV had been the most studied coronavirus both in vivo and in vitro, as well as at the molecular level. Some strains of MHV cause a progressive demyelinating encephalitis in mice which has been used as a murine model for multiple sclerosis.
Detoxification of all Coronavirus and related species
Detoxification of all Hepatitis A-E and related species
Detoxification of all Influenza and related species
Detoxification of Measles and related species