Endolimax is a genus of amoebozoa found in the intestines of various animals and humans. Originally thought to be non-pathogenic, studies suggest it can cause intermittent or chronic diarrhea. It is very significant in medicine because it can provide false positives for other tests, such as the similar species Entamoeba histolytica (the pathogen responsible for amoebic dysentery), and because its presence indicates the host has consumed fecal material.

Similar to other parasites acquired through the fecal-oral route, symptoms include diarrhea, bloating and abdominal pain.