The Rickettsia survival depends on entry, growth, and replication within host cells (typically endothelial cells). Rickettsia species are carried by ticks, fleas, and lice, and cause diseases in humans such as typhus, rickettsialpox, Boutonneuse fever, African tick bite fever, Rocky Mountain spotted fever, Flinders Island spotted fever and Queensland tick typhus (Australian Tick Typhus). They have also been associated with a range of plant diseases.

Despite the similar name, Rickettsia bacteria do not cause rickets, which is a result of vitamin D deficiency.

This Quantum Formula antidotes the various species in the Rickettsia genus and all of its subspecies.